Influence of Family History Classifications in Cataract Occurrence Rate Among Local Residence of Imo State
Abstract
Cataract is one of leading causes of visual impairments around the globe which is associated with genetic factors. The present study was designed as a descriptive cross-sectional study aimed at assessing the influence of family history classifications on cataract occurrence rate among adult residents in Imo State Nigeria. A multi-stage sampling method was used to sample 792 study participants across the state of study. The presence of cataract was established using Lens Opacity Classification System (LOCS) III system. A slit lamp examination was performed to assess the severity of specific lens opacity. The participants were also assessed of family history of cataract using a study designed self-reported forms. Family history was classified into direct or first-degree relatives and indirect or second-degree relatives. The characteristics of the participants was described using statistical descriptive analysis technique such as frequency distribution table. Chi-square test was used to test for association between family history and occurrence of cataract. Further analysis includes logistic regression method used to compare the significant effects of factors of family history relatives. The results indicates that 200 (25.3%) reported having family history relatives with cataract. Significant association was found between cataract and family history (P=0.0001, ?2=73.42), with 98% lower odds found among the non-family history reported group (OR =0.022, 95% CI =0.0025 – 0.0883). Interns of classifications of family history relatives, cataract was found highest among the direct or first-degree family relatives. It was also found to be most occurring if the family relative reported was a sister or a brother with up to four time more significant odds compared to non-direct relatives (OR= 4.11, 95% CI =1.040 – 16.331). In conclusion, family history is significantly associated with cataract and contained greater risk among direct relatives such as brothers/ sister relatives. Detailed family history of cataracts classifications should adequately studied to identify the classes of familial cases at greater risk so as to minimise cost and enable the benefit from merits attached to early detection and treatments for the disease.
Keywords
Cataract, Visual Impairment, Family History, Direct Relatives
Citations
IRE Journals:
Tochukwu Increase Obianozie , Stanley James Ozims , Izuchukwu Francis Eberendu , Greg Ndubeze Iwuoha , Chike C. A. Okereke
"Influence of Family History Classifications in Cataract Occurrence Rate Among Local Residence of Imo State" Iconic Research And Engineering Journals Volume 8 Issue 9 2025 Page 1389-1395
IEEE:
Tochukwu Increase Obianozie , Stanley James Ozims , Izuchukwu Francis Eberendu , Greg Ndubeze Iwuoha , Chike C. A. Okereke
"Influence of Family History Classifications in Cataract Occurrence Rate Among Local Residence of Imo State" Iconic Research And Engineering Journals, 8(9)
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