Recent Developments in Tuberculosis Diagnosis, Treatment, and Control Strategies: A Global Overview
Abstract
Tuberculosis (TB) remains a significant global health challenge, particularly in resource-limited settings, where it disproportionately affects vulnerable populations. This review explores recent advancements in TB diagnosis and treatment, focusing on innovative strategies for both drug-sensitive and drug-resistant forms. A systematic search of relevant literature was conducted using databases such as PubMed, Scopus, and Web of Science, selecting studies published from 2015 to 2023 that report on TB diagnostic and treatment advancements. Advances in molecular diagnostics, such as the GeneXpert MTB/RIF, have revolutionized TB detection, enabling rapid and accurate identification of the disease and its drug-resistant strains. In terms of treatment, shorter and more effective drug regimens have emerged, enhancing adherence and improving patient outcomes. Notable developments include bedaquiline and delamanid for multidrug-resistant TB (MDR-TB), alongside the novel BPaL regimen, which combines pretomanid, bedaquiline, and linezolid, demonstrating high cure rates. Public health strategies, including active case finding and community-based treatment, are critical for curtailing transmission and addressing social determinants of health. This review also discusses ongoing research into vaccines, which are essential for preventing TB, particularly in high-risk populations. Despite the progress made, challenges remain in ensuring access to newer treatments in low-resource settings and addressing the rise of drug-resistant strains. This review provides a comprehensive overview of the current landscape in TB management and control, emphasizing improved treatment options and collaborative efforts necessary for enhanced patient outcomes and global TB eradication.
Keywords
Tuberculosis, Diagnosis, Treatment, Drug Resistance, Public Health Strategies
Citations
IRE Journals:
Dr Uzair Vohra , Dr Darpan Agrawal , Dr Shrey Chaudhari , Dr Huma Khan
"Recent Developments in Tuberculosis Diagnosis, Treatment, and Control Strategies: A Global Overview" Iconic Research And Engineering Journals Volume 8 Issue 6 2024 Page 880-884
IEEE:
Dr Uzair Vohra , Dr Darpan Agrawal , Dr Shrey Chaudhari , Dr Huma Khan
"Recent Developments in Tuberculosis Diagnosis, Treatment, and Control Strategies: A Global Overview" Iconic Research And Engineering Journals, 8(6)
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IRE Journals is an open access online journals established with an aim to publish high quality of research work in various diciplines. We have more than 6 years in publications. Over 2500+ papers already published.
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