Abstract
This review offers a comprehensive analysis of biodegradable nanoparticles, emphasizing their biocompatibility, adaptability, and customizable characteristics, which render them ideal for drug delivery applications. It discusses various preparation techniques for biodegradable nanoparticles, through the polymerization of monomers and dispersion of preformed polymers, including solvent evaporation, solvent diffusion, nanoprecipitation, and electros praying methods, highlighting their utility in targeted drug delivery applications. The review also examines therapeutic nanoparticles and different classes of therapeutic nanoparticles, including polymer-based nanoparticles, non-polymeric nanoparticles and lipid-based nanoparticles, detailing their unique properties and significant role in optimizing drug delivery systems. It further explores strategies for drug incorporation into nanoparticles—encompassing encapsulation, surface adsorption, and chemical conjugation techniques—and investigates their release mechanisms and applications in targeted drug delivery.
Keywords
Nanotechnology, Therapeutic nanoparticles, Drug Delivery Systems, Encapsulation, Electrospray
Citations
IRE Journals:
Michael Adeniyi , Peculiar Lawrence
"Nanoparticles for Therapeutic Use and Targeted Drug Delivery Applications" Iconic Research And Engineering Journals Volume 7 Issue 5 2023 Page 318-331
IEEE:
Michael Adeniyi , Peculiar Lawrence
"Nanoparticles for Therapeutic Use and Targeted Drug Delivery Applications" Iconic Research And Engineering Journals, 7(5)
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IRE Journals is an open access online journals established with an aim to publish high quality of research work in various diciplines. We have more than 6 years in publications. Over 2500+ papers already published.
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