Synthesis and Antibacterial Activities of 2-amino-N-(p-Chlorophenyl) acetamide derivatives
  • Author(s): Yuh-Wern Wu ; Jyh-Ferng Yang ; Li-Yeh Chuang ; Jian-Fong Huang
  • Paper ID: 1702353
  • Page: 144-147
  • Published Date: 20-06-2020
  • Published In: Iconic Research And Engineering Journals
  • Publisher: IRE Journals
  • e-ISSN: 2456-8880
  • Volume/Issue: Volume 3 Issue 12 June-2020
Abstract

As eries of 2-amino-N-(p-Chlorophenyl) acetamide derivatives (5a ~ 5d) were synthesized by the reaction of 2-bromo-N-(p-Chlorophenyl) acetamide (3) with various amine (4a ~ 4d) at room temperature. The antibacterial activities of all the compounds were evaluated againstfour bacterial strains(Acinetobacter baumannii, Pseudomonas aeruginosa andStaphylococcus aureus)and showed moderate to high activities.

Keywords

N-phenylacetamide, Antibacterial Activity, Synthesis.

Citations

IRE Journals:
Yuh-Wern Wu , Jyh-Ferng Yang , Li-Yeh Chuang , Jian-Fong Huang "Synthesis and Antibacterial Activities of 2-amino-N-(p-Chlorophenyl) acetamide derivatives" Iconic Research And Engineering Journals Volume 3 Issue 12 2020 Page 144-147

IEEE:
Yuh-Wern Wu , Jyh-Ferng Yang , Li-Yeh Chuang , Jian-Fong Huang "Synthesis and Antibacterial Activities of 2-amino-N-(p-Chlorophenyl) acetamide derivatives" Iconic Research And Engineering Journals, 3(12)